Chinwiwa chinonzi 5-hydroxytryptophan (5-HTP) kana osetriptan chinoonekwa seimwe yenzira dzekurapa misoro nemusoro. Muviri unoshandura chinhu ichi kuita serotonin (5-HT), inozivikanwawo se serotonin, neurotransmitter inodzora manzwiro nemarwadzo.
Kuderera kweserotonin kunowanzoonekwa muvanhu vane kushungurudzika, asi vanorwara nemigraine nevane musoro usingaperi vanogonawo kuwana kuderera kweserotonin panguva yekurwiswa uye pakati pekurwiswa. Hazvizivikanwe kuti sei migraine neserotonin zvakabatana. Dzidziso inonyanya kufarirwa ndeyekuti kushomeka kweserotonin kunoita kuti vanhu vanzwe kurwadziwa zvakanyanya.
Nekuda kwekubatana uku, nzira dzakasiyana-siyana dzekuwedzera kushanda kweserotonin muuropi dzinowanzo shandiswa kudzivirira migraines uye kurapa kurwiswa kwakanyanya.
5-HTP iamino acid inogadzirwa nemuviri kubva kuL-tryptophan inokosha uye inofanira kuwanikwa kubva muchikafu. L-tryptophan inowanikwa muzvikafu zvakaita sembeu, soya, turkey nechizi. Ma enzyme anoshandura L-tryptophan kuita 5-HTP, iyo inozoshandura 5-HTP kuita 5-HT.
Mishonga yekuwedzera ye5-HTP inogadzirwa kubva kuchirimwa chekurapa cheWest Africa chinonzi Griffonia simplicifolia. Iyi mishonga yekuwedzera yakashandiswa kurapa kuora mwoyo, fibromyalgia, chronic fatigue syndrome, uye kuderedza uremu, asi hapana humbowo hwakajeka hwekubatsira kwayo.
Paunenge uchifunga nezve 5-HTP kana chero chimwe chinhu chechisikigo, zvakakosha kunzwisisa kuti zvigadzirwa izvi makemikari. Kana ukazvitora nekuti zvine simba rekubatsira hutano hwako, yeuka kuti zvinogonawo kuva nesimba rekubatsira hutano hwako.
Hazvisi pachena kana mishonga ye5-HTP inobatsira pakurwadziwa kwemusoro kana mamwe marudzi emusoro. Pakazara, tsvakiridzo ishoma; zvimwe zvidzidzo zvinoratidza kuti zvinobatsira, nepo zvimwe zvisingaratidzi kushanda.
Zvidzidzo zvemigraine zvakashandisa madosi e5-HTP anotangira pa25 kusvika 200 mg pazuva kuvanhu vakuru. Parizvino hapana dosi yakajeka kana inokurudzirwa yemushonga uyu, asi zvakakosha kuziva kuti madosi akakwira ane chekuita nemigumisiro uye kusangana kwemishonga.
5-HTP inogona kushanda pamwe chete nemimwe mishonga, kusanganisira carbidopa, iyo inoshandiswa kurapa chirwere cheParkinson. Inogona kushandawo pamwe chete ne triptans, SSRIs, uye monoamine oxidase inhibitors (MAOIs, rimwe boka remishonga inorwisa kushushikana kwepfungwa).
Mishonga yeTryptophan ne5-HTP inogona kunge yakasvibiswa nechigadzirwa chechisikigo che4,5-tryptophanione, chirwere chepfungwa chinozivikanwawo sePeak X. Kuzvimba kwePeak X kunogona kukonzera kurwadziwa kwetsandanyama, kurwadziwa kwemakumbo, uye fivha. Mhedzisiro yenguva refu inogona kusanganisira kukuvara kwetsandanyama netsinga.
Nekuti kemikari iyi inokonzerwa nemakemikari uye haisi tsvina kana chinhu chinosvibisa, inogona kuwanikwa muzvinowedzera zvekudya kunyangwe kana zvakagadzirwa mumamiriro ehutsanana.
Zvakakosha kukurukura nezvekushandisa mishonga yekuwedzera nachiremba wako kana wemishonga kuti uve nechokwadi chekuti haina njodzi kwauri uye haizosangani nemimwe mishonga yako.
Rangarirai kuti mishonga yekuwedzera mune zvekudya neyemishonga yemishonga haina kuongororwa zvakanyanya uye kuyedzwa kwakafanana nekwemishonga inotengeswa kunze kwechitoro chemishonga uye inonyorerwa nachiremba, zvichireva kuti tsvakiridzo inotsigira kushanda kwayo uye kuchengetedzeka kwayo haina kukwana kana kuti haina kukwana.
Mishonga yekuwedzera uye mishonga yechisikigo inogona kukwezva, kunyanya kana isina migumisiro yakaipa. Kutaura zvazviri, mishonga yechisikigo yaratidza kuti inoshanda pazvirwere zvakawanda. Pane humbowo hwekuti magnesium supplements inogona kuderedza kuwanda uye kuoma kwekurwiswa kwemigraine. Zvisinei, hazvizivikanwe kana 5-HTP ichibatsira migraine.
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Teri Robert Teri Robert munyori, mudzidzisi wevarwere, uye mutsigiri wevarwere anonyanya kurapa migraines nemusoro.