Muviri wako unoushandisa kugadzira serotonin, kemikari messenger inotumira masaini pakati pemasero etsinga.
Low serotonin yakabatanidzwa nekuora mwoyo, kuzvidya mwoyo, kukanganisa kurara, kuwedzera uremu, uye mamwe matambudziko ehutano (1, 2).
Kurasikirwa uremu kunowedzera kugadzirwa kwemahomoni anokonzera nzara.Uku kunzwa nzara nguva dzose kunogona kuita kuti uremu husagadzirike mukufamba kwenguva (3, 4, 5).
5-HTP inogona kupikisa aya mahomoni anokonzera nzara anodzvinyirira kudya uye kukubatsira kuderedza uremu (6).
Mune imwe ongororo, varwere makumi maviri vane chirwere cheshuga vakapihwa zvisina tsarukano kuti vagamuchire 5-HTP kana placebo kwemavhiki maviri.Mhedzisiro yakaratidza kuti avo vakagamuchira 5-HTP vakadya anenge 435 mashoma macalorie pazuva zvichienzaniswa neboka re placebo (7).
Uyezve, 5-HTP inonyanya kudzvinyirira kudya kwemakhahydrates, iyo inosanganiswa nepamusoro glycemic control (7).
Zvimwe zvidzidzo zvakawanda zvakaratidzawo kuti 5-HTP inowedzera satiety uye inosimudzira kurasikirwa nehuremu muvanhu vakafuta kana vakafutisa (8, 9, 10, 11).
Mukuwedzera, zvidzidzo zvemhuka zvakaratidza kuti 5-HTP inogona kuderedza kudya kwakanyanya kwekudya nekuda kwekunetseka kana kuora mwoyo (12, 13).
5-HTP inogona kushanda mukuwedzera satiety, iyo inogona kukubatsira kudya zvishoma uye kuderedza uremu.
Kunyange zvazvo chikonzero chaicho chekuora mwoyo chisingazivikanwe, vamwe vatsvakurudzi vanotenda kuti kusaenzana kwe serotonin kunogona kukanganisa mafungiro ako, zvichiita kuti uderedze mwoyo (14, 15).
Kutaura zvazviri, zvidzidzo zviduku zvishoma zvakaratidza kuti 5-HTP inogona kuderedza zviratidzo zvekuora mwoyo.Zvisinei, vaviri vavo havana kushandisa placebo kuenzanisa, izvo zvakaderedza kutendeseka kwemigumisiro yavo (16, 17, 18, 19).
Zvisinei, zvidzidzo zvakawanda zvakaratidza kuti 5-HTP ine simba rakasimba rekugadzirisa dambudziko kana richishandiswa pamwe chete nezvimwe zvinhu kana antidepressants kupfuura kana inoshandiswa yoga (17, 21, 22, 23).
Mukuwedzera, ongororo dzakawanda dzakagumisa kuti kumwe kutsvagisa kwemhando yepamusoro kunodiwa pamberi pe5-HTP inogona kukurudzirwa kurapwa kwekuora mwoyo (24, 25).
5-HTP zvinowedzera kuwedzera mazinga e serotonin mumuviri, izvo zvinogona kubvisa zviratidzo zvekuora mwoyo, kunyanya kana zvakasanganiswa nemamwe antidepressants kana mishonga.Zvisinei, kutsvakurudza kwakawanda kunodiwa.
5-HTP yekuwedzera inogona kuvandudza zviratidzo zve fibromyalgia, chirwere chinoratidzwa nekurwadziwa kwemhasuru uye pfupa uye kushaya simba kwakawanda.
Parizvino hapana chinozivikanwa chikonzero chefibromyalgia, asi yakaderera serotonin mazinga akabatanidzwa kune iyo mamiriro (26Trusted Source).
Izvi zvinotungamira vaongorori kuti vatende kuti kuwedzera serotonin mazinga ane 5-HTP ekuwedzera anogona kubatsira vanhu vane fibromyalgia (27).
Muchokwadi, humbowo hwekutanga hunoratidza kuti 5-HTP inogona kuvandudza zviratidzo zve fibromyalgia, kusanganisira kurwadziwa kwemasuru, matambudziko ekurara, kunetseka, uye kuneta (28, 29, 30).
Zvisinei, hapana tsvakurudzo yakakwana yakaitwa kuti iite chero mhedziso dzakasimba pamusoro pekushanda kwe5-HTP mukuvandudza zviratidzo zve fibromyalgia.
5-HTP inowedzera serotonin mazinga mumuviri, izvo zvinogona kubvisa zvimwe zvezviratidzo zve fibromyalgia.Zvisinei, kutsvakurudza kwakawanda kunodiwa.
5-HTP inonzi inobatsira kubata migraines, rudzi rwemusoro unowanzoperekedzwa nekusvotwa kana kukanganiswa kwekuona.
Kunyange zvazvo chikonzero chavo chaicho chichikakavadzana, vamwe vatsvakurudzi vanotenda kuti zvinokonzerwa nemazinga akaderera e serotonin (31, 32).
Chidzidzo chevanhu vane 124 chakaenzanisa kukwanisa kwe5-HTP uye methylergometrine, mishonga yakajairika yemigraine, kudzivirira migraine misoro (33).
Chidzidzo chakawana kuti kutora 5-HTP zuva nezuva kwemwedzi mitanhatu kwakadzivirira kana kuderedza zvakanyanya nhamba yekurwisa migraine mu71% yevatori vechikamu (33).
Mune chimwe chidzidzo chevadzidzi ve48, 5-HTP yakaderedza kuwandisa kwemusoro ne70% kana ichienzaniswa ne11% muboka re placebo (34).
Saizvozvowo, zvimwe zvidzidzo zvakawanda zvakaratidza kuti 5-HTP inogona kuva mushonga unoshanda wemigraines (30, 35, 36).
Melatonin inoita basa rinokosha pakugadzirisa kurara.Matanho ayo anotanga kusimuka husiku kukurudzira kurara uye kudonha mangwanani kuti akubatsire kumuka.
Naizvozvo, 5-HTP yekuwedzera inogona kukurudzira kurara nekuwedzera kugadzirwa kwe melatonin mumuviri.
Chidzidzo chevanhu chakawana kuti kusanganiswa kwe5-HTP uye gamma-aminobutyric acid (GABA) yakaderedza zvakanyanya nguva inotora kurara, kuwedzera nguva yekurara, nekuvandudza kurara kwehutano (37).
GABA ikemikari messenger inokurudzira kuzorora.Kuibatanidza ne5-HTP inogona kunge iine synergistic effect (37).
Muchokwadi, akati wandei mhuka uye zvipembenene zvidzidzo zvakaratidza kuti 5-HTP inovandudza kurara kunaka uye iri nani kana yakasanganiswa neGABA (38, 39).
Kunyange mhedzisiro iyi ichivimbisa, kushaikwa kwezvidzidzo zvevanhu kunoita kuti zviome kukurudzira 5-HTP yekuvandudza kunaka kwekurara, kunyanya kana ichishandiswa chete.
Vamwe vanhu vanogona kunzwa kusvotwa, manyoka, kurutsa, uye kurwadziwa mudumbu vachitora 5-HTP yekuwedzera.Iyi mhedzisiro inotsamira pamushonga, zvichireva kuti ivo vanotowedzera sezvo dosi rinowedzera (33).
Kuti uderedze mhedzisiro iyi, tanga nemuyero we50-100 mg kaviri zuva rega rega uye uwedzere kune imwe yakakodzera dose kwemavhiki maviri (40).
Mimwe mishonga inowedzera kugadzirwa kwe serotonin.Kubatanidza mishonga iyi ne5-HTP kunogona kukonzera mazinga ane ngozi e serotonin mumuviri.Izvi zvinodaidzwa kuti serotonin syndrome, iyo inogona kuisa hupenyu panjodzi (41).
Mishonga inogona kuwedzera mazinga e serotonin mumuviri inosanganisira mamwe antidepressants, mishonga yechikosoro, kana mishonga inoderedza marwadzo.
Nekuti 5-HTP inogonawo kukurudzira kurara, kuitora nemishonga inorarisa yakadai seKlonopin, Ativan, kana Ambien inogona kukonzera kurara zvakanyanya.
Nekuda kwekugona kusawirirana kwakashata nemimwe mishonga, bvunza chiremba wako kana wemishonga usati watora 5-HTP yekuwedzera.
Paunenge uchitenga zvekuwedzera, tsvaga NSF kana USP zvisimbiso zvinoratidza mhando yepamusoro.Aya ndiwo makambani ebato rechitatu anovimbisa kuti ma supplements ane izvo zvakataurwa pane iyo label uye haana tsvina.
Vamwe vanhu vanogona kusangana nemhedzisiro kana vachitora 5-HTP yekuwedzera.Tarisa nachiremba wako usati watora 5-HTP kuti uone kuti yakachengeteka kwauri.
Izvi zvinowedzera zvakasiyana neL-tryptophan zvinowedzera, izvo zvinogonawo kuwedzera serotonin mazinga (42).
L-tryptophan inokosha amino acid inowanikwa mune mapuroteni-akapfuma zvekudya zvakadai semukaka, huku, nyama, chickpeas, uye soya.
Kune rimwe divi, 5-HTP haiwanikwe muchikafu uye inogona kungowedzerwa mukudya kwako kuburikidza nekudya kwekuwedzera (43).
Muviri wako unoshandura 5-HTP kuita serotonin, chinhu chinodzora kudya, kuona kurwadziwa, uye kurara.
Yakakwira serotonin mazinga anogona kuve nemabhenefiti akawanda, akadai sekuonda, kurerukirwa kubva kuzviratidzo zvekuora mwoyo uye fibromyalgia, kuderedzwa kuwanda kwekurwiswa kwemigraine, uye kurara zviri nani.
Mishonga midiki yakabatanidzwa ne5-HTP, asi izvi zvinogona kudzikiswa nekutanga nediki dosi uye zvishoma nezvishoma kuwedzera muyero.
Tichifunga kuti 5-HTP inogona kudyidzana zvisina kunaka nemimwe mishonga, tarisa nachiremba wako kuti uone kuti yakachengeteka kwauri.
Nyanzvi dzedu dzinogara dzichitarisa hutano uye hutano nzvimbo uye kugadzirisa zvinyorwa zvedu sezvo ruzivo rutsva runowanikwa.
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