1. Endothelin vanopikisa

Inotorwa kubva kuEuropean herb chamomile, iyo inogona kuramba endothelin uye inhibisa kugadzirwa kwe melanocytes. Kugoverwa kusina kuenzana kwe endothelin muganda ndicho chinhu chikuru chinotungamira pakuumbwa kwepigmentation. Endothelin vanopikisa vanogona kudzivisa endothelin.. tyrosinase uye kukurudzira kusiyanisa kwe melanocytes.

Zvidzidzo zvakawana kuti endothelin antagonists akatorwa kubva kune zvipenyu zvemvura ane yakaderera cytotoxicity uye anogona kutadzisa kusiyanisa endothelin pa melanocytes uye basa re tyrosinase. Skin hyperpigmentation zvirwere zvinokonzerwa nekuwedzera -l inogona kunge ine tarisiro yekushandisa.

2. Resveratrol uye zvinobva mairi

Resveratrolinonyanya kuwanikwa mumazambiringa, Polygonum cuspidatum, Veratrum uye zvimwe zvirimwa, uye inhibits basa re melanocytes uye basa re tyrosinase nenzira inotsamira, nokudaro kuderedza melanin synthesis. Jeong et al akawana kuti inobatanidzwawo nemapuroteni ane hukama ne tyrosinase mu melanogenesis.

Jia Lili uye zvimwe zvidzidzo zvakaratidza kuti topical resveratrol inogona kunyatso kuvandudza ruvara rweganda, ine kumwe kuchena mhedzisiro, uye haina maitiro akaipa. Resveratrol ine zvakaipira kusagadzikana uye kushata bioavailability. Zvidzidzo zvakawana kuti zvinobva pairi (pentaalkyl ether derivatives uye tetraester derivatives) zvine bioavailability yakakwira uye inogona kudzivirira zvirinani kuumbwa kwe melanin. Iine tarisiro yakafara yekushandiswa mukuchenesa cosmetics.

3. Camellia Extract

Camellia imhando yeCamellia yemhuri yeCamellia. Nakamura et al. akawana kuti camellia maruva bud inobvisa inogona kurambidza kugadzirwa kwe melanin uye kukurudzira kusiyanisa kwe fibroblast. Huang Xiaofeng uye zvimwe zvidzidzo zvakagumisa kuti Dhianshan tii bazi uye mashizha anotorwa zviri nani pane arbutin maererano nekuwedzera kwesero uye inhibition ye tyrosinase chiitiko, uye ine zvivakwa zviri nani pane arbutin. Irwo rudzi rutsva rweganda rinochenesa mumiririri uye rine zvakawanda zvakasiyana-siyana zvekushandisa. tarisiro.

MelaninSynthaseInhibitor

1. Arbutin

Iyo yakakosha tyrosinase inhibitor, inogona kutadzisa kuita kwe tyrosinase, ichivharira synthesis ye dopa uye dopaquinone, nekudaro ichitadzisa kugadzirwa kwe melanin, uye inogona zvakare kuderedza zvakanyanya pigmentation inokonzerwa ne ultraviolet rays, asi yakagadzikana Kusashanda zvakanaka, pamwe nezvimwe. photosensitivity.

Chidzidzo chacho chakawana kuti arbutin ine mutsara we3% ine yakanaka zvivakwa, yakaderera cytotoxicity, kushatirwa uye allergies, uye muganho wepamusoro wekusungwa kwayo haugone kudarika 7%. Kuwanda kwe arbutin kuchaita decolorize ganda rakajairwa. Chigadzirwa chayo chechisikigo chinoshanda, glucopyranoside, ine inhibitory yakasimba pamunhu tyrosinase kupfuura arbutin, uye inotsiva arbutin nekuti inoshanda uye yakagadzikana.

2. Licorice Extract

Zvishandiso zvayo zvinoshanda zvakanyanya liquiritin, isoliquiritin uye licorice flavonoids. Liquiritin inoita kuti ganda melanin rigovane zvakaenzana nekuparadzira yakaunganidzwa melanin, uye inowana chena mhedzisiro; basa guru re licorice flavonoids nderokudzivisa basa re tyrosinase, DHICA oxidase uye dopa pigment intermutase.

Zvidzidzo zvakawana kuti zvigadzirwa zvekuchengetedza ganda zvine licorice inobvisa uye papain zvinogona kubatsira melasma uye post-ekuzvimba hyperpigmentation, ine mashoma maitiro akaipa, uye ine zvimwe .. uye .. zvivakwa. Kuiswa kwayo muzvigadzirwa zvekuchena ndeye 10% kusvika 40%, asi zvirimo zvezvishandiso zvinoshandiswa mu licorice hazvina kukwirira uye kucheneswa kwakaoma uye kunodhura.

3. Chuanxiong Extract

Zvidzidzo zvakawana kuti Chuanxiong yakatorwa inogona kunyatso kuvharidzira chiitiko che tyrosinase, ichiratidza kukwikwidza inhibitory mhedzisiro. Chizoro cheChuanqiong chakagadzirwa kuburikidza neforoma yekomboni yema emulsifiers akasiyana uye makobvu akasiyana, tsvakiridzo pamusoro pekushanda kwayo kuchena uye kuita kwakaratidza kuti 0.5% ~ 1.0% Chuanqiong mafuta ane hunhu hwekugadzikana kwakanaka, kuita kwepamusoro uye kuchena kwakanaka .

4. Rhodiola Rosea Extract

Salidroside uye flavonoids ndiyo inonyanya kushanda zvikamu, uye salidroside inogona kukuvadza lipids uye cell membranes nemirairo ye ultraviolet. Iyo inobvisa inogona kuvharidzira synthesis ye melanin uye basa re tyrosinase, uye inoshanda chena ganda mumiriri. Chidzidzo ichi chakawana kuti 1% uye 5% yeRhodiola rosea yakatorwa haina kukonzera kukanganisa mumuviri wemunhu, uye iri cosmetic inoshanda chimedu ine kugadzikana kwepamusoro uye ine tarisiro yakakura mukushandisa zvizorwa.

5. Aloin

Iyo yakaderera molecular huremu chirimwa glycoprotein yakatorwa kubva mualoe vera. Iyo inonyanya kurambidza kuumbwa kwedopaquinone nemakwikwi inhibiting iyo dopa oxidation site, uye inobudirira isina kukwikwidza inhibition nemakwikwi inhibiting ions yemhangura panzvimbo yehydroxylase. Basa re tyrosine hydroxylase. Mukuwedzera, aloin inogonawo kuderedza kusviba kweganda kunokonzerwa nemirairo ye ultraviolet, uye ine maitiro akanaka ekugadzirisa paganda mushure mekubuda kwezuva. Aloin is hydrophilic uye isiri-cytotoxic. Kusanganisa aloin ne arbutin kunogona kuvandudza chena mhedzisiro.

6. Plant Polyphenols

Inonyanya kuwanikwa mumakwati, midzi, mashizha uye michero yemiti, uye kuchena kwayo kunonyanya kuenderana nekutora kwayo ultraviolet rays, antioxidant kubviswa kwemahara radicals, uye inhibition ye tyrosinase uye peroxidase zviitiko. Ellagic asidhi ndeye yakasikwa polyphenol yakatorwa kubva mumapomegranate peel, bark uye akasiyana michero nemiriwo. Inogona kudzivisa kupararira kwe melanocytes, inhibit basa re melanocyte tyrosinase, kuderedza melanin synthesis, Ultraviolet rays ine simba rakasimba rekunyura, iyo inogona kuita basa mukudzivirira kwezuva kana kuchenesa mahara radicals nekutora ultraviolet rays. Plant polyphenol imhando yechinhu chinoshanda, ine tarisiro yakakura yekuvandudza uye kushandiswa kwezvizoro.

Contact details:
Shaanxi Ruiwo Phytochem Co., Ltd.
Overseas Manager: Jason
Mhomho: 0086-18629669868
Email:jason@ruiwophytochem.com
Whatsapp: 008618629669868