1. The Abstract of Aframomum Melegueta

TheAframomum Melegueta, akaberekerwa kuWest Africa, ane kadhiamomu uye kunhuwirira kwemhiripiri. Yakashandiswa zvakafara sechinotsiva apo mhiripiri yakanga iri shoma muEurope muzana ramakore rechi 13, uye yainzi “mbeu yokudenga” nemhaka yokuti yairangarirwa kuva nyasha dzinobva kudenga.

Aframomum Melegueta ine mazita akasiyana sezviyo zveparadhiso, Atare (muYoruba), chitta (Hausa), kana Guinea pepper, imbeu imwe ine simba rekuporesa rakawanda uye mabhenefiti ayo kuvanhu anoita seasingaperi.

Aframomum melegueta (Zviyo zveParadhiso) iri kushandiswa kurapa zvirwere zvinotapukira zvakadai sehutachiona hwehutachiwana hunokonzerwa neEscherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Staphylococcus saprophyticus, Proteus mirabilis, methicillinresistant auregeusscoccus, methicillin resistant Staphyloppnellas, Salmogellappne, Salmoss, Salmoss, Salmonella, uye Staphylococcus faecalis. Inoratidza chimwe chivimbiso mukudzora kwemafuta-huwandu pamadosi anogona kudyiwa muzvigadzirwa zvekudya uye musanganiswa wemishonga.

2.Distribution Area

Aframomum Melegueta(Paradise Pepper), ane zita chairo anonzi African Cardamom, anozivikanwawo sePeppercorn, Guinea Pepper, Melegueta Mhiripiri, Paradise Pepper, kana Alligator Pepper, chirimwa chisingaperi chemhuri yeZingiberaceae. Inowanikwa kumachakwi emahombekombe eWest Africa. Inovhura maruva eruvara rwepepuru, yakaita sehwamanda, inobereka mapodhi akareba 5-7 cm uye ine mhodzi dzakatsvuka-tsvuku. Peppery, zvakare nekuti yakave yekutanga pepper inotsiva. Ikozvino inongowanikwa mukushandiswa kwemukati muAfrica. Ndiyo imwe Silk Road spice yakanyangarika kubva kuEurasian cuisine yemazuva ano, asi ichiri kushandiswa munzvimbo dzekuMadokero neNorth Africa, uye chirimwa chakakosha chemari mune dzimwe nzvimbo dzeEthiopiya. African cardamom, iyo inowanikwa munzvimbo dziri mumhenderekedzo yegungwa kumadokero kweAfrica, inoratidzika kuva yakashandiswa pedyo neGhana yazvino uno pakutanga uye gare gare yakatumirwa kune dzimwe nzvimbo dzechiteshi chengarava dziri kumabvazuva kweAfrica kana kuti kumhenderekedzo yeMediterranean kunotengeserana nomuSirika Road. Iyo inonhuwira, iyo yakanga iri hasha mukubika kweEurope munguva yekutanga Renaissance, zvishoma nezvishoma yakapera kubva patafura nezana remakore rechigumi nemasere uye yakabva yanyangarika kubva kumisika yeEurope, yakatsiviwa ne cardamom nezvimwe zvinonhuwira zvakatengeswa kubva kuAsia pasi rose.

3. Nhanganyaya ye6-Paradol

Paradol, isiri-pungent metabolite ye shogaol nekuderedza enzymatic, inozivikanwa kuve ine anti-kuzvimba zviitiko. Izvozvi mu vitro zvakawanikwa zvinoratidza kuti inhibitory properties ye6-paradol mukurapa neuroinflammation mu microglia correlates kune in vivo therapeutic potential for cerebral ischemia. 6-paradol's neuroprotective efficacy mu cerebral ischemia inewo inogona kushandiswa mukurapa kweimwe CNS kusagadzikana umo neuroinflammation chinhu che pathological. Mukuwedzera, kana 6-paradol inoratidzwa kuti inoshanda mune mamwe matambudziko eCNS, pfuma yayo isiri-pungent ine mukana wezvishoma zvinokonzerwa nemudumbu, izvo zvinoreva kuti inogona kutorwa kwenguva refu, kusiyana neiyo ginger kana zvikamu zveginger. zvichida 6-shogaol.

6-paradolinorwisa marariya ine simba zvakanyanya uye chikamu chikuru cheZoyechipirimetabolite dziva.

6-Paradol (zita reIUPAC [1-(4-hydroxy-3-methoxyphenyl) decan-3-one]) inonzi pungent phenolic compound inowanikwa mumiti yemhuri yeZingiberaceae, yakadai seginger uye zviyo zveparadhiso (Aframomum meleguetakana alligator mhiripiri). Sezvakataurwa kune imwe nzvimbo, zvidzidzo zvishomanana zvakashuma iyo antioxidant, anti-inflammatory, cytotoxic, anti-hyperlipidaemic, hypoglycaemic, uye antitumour mabasa emhando dzakasiyana dzeparadol mumhando dzakasiyana dzemhuka.